What causes Keratoglobus?
Causes of Keratoglobus may be: Congenital: Keratoglobus is primarily considered a congenital disorder present since birth. The congenital form of the disorder is always bilateral. The exact genetics of the disorder have not been studied in detail and no definite inheritance pattern has been described.
Is Keratoglobus progressive?
Keratoglobus is considered a non-progressive or minimally progressive disorder. The corneal thinning in keratoconus is most commonly seen in the inferior paracentral aspect of the cornea. The protrusion is commonly described as conical in shape, with maximal thinning at the apex.
How common is Keratoglobus?
Keratoglobus is a rare, noninflammatory corneal ectasia characterized by diffuse protrusion and thinning of the cornea.
Is Keratoglobus congenital?
Keratoglobus may be associated with blue sclera, hyperextensibility of the joints or auditory problems. Most often it is a congenital disease with autosomal recessive transmission, but it may be secondarily acquired to an advanced keratopathy (keratoconus), to trauma or to exophthalmos.
What is dystrophy of the eye?
Corneal dystrophies are eye diseases that involve changes in the cornea (the clear front layer of your eye). These diseases usually run in families. Most corneal dystrophies are progressive — they get worse over time. Some cause vision loss or pain, but some have no symptoms.
What does Microcornea mean?
Definition. A congenital abnormality of the cornea in which the cornea and the anterior segment of the eye are smaller than normal.
What causes corneal opacity?
Corneal opacity occurs when the cornea becomes scarred. This stops light from passing through the cornea to the retina and may cause the cornea to appear white or clouded over. Common causes include Infection, injury, corneal abrasion or scratch or swelling of the eye.
What causes corneal hydrops?
Acute corneal hydrops is believed to result from a break in Descemet membrane and the endothelium, leading to an influx of aqueous humor into the stroma and subsequent formation of corneal edema.
What is the best treatment for endothelial dystrophy?
Your doctor may recommend a partial-thickness cornea transplant, a procedure known as Descemet-stripping endothelial keratoplasty (DSEK). Rarely, a full-thickness cornea transplant, known as penetrating keratoplasty (PK), may be recommended.
What causes Microcornea?
It is thought that microcornea occurs secondary to an arrest in corneal development due to overgrowth of the tips of the optic cup.
What is the best surgical treatment for keratoglobus?
Surgical management of keratoglobus is challenging. Various techniques have been proposed, but a gold standard has not yet emerged. Traditional penetrating keratoplasty (PK) was one of the first surgical procedures attempted. It has the advantage of being less technically difficult than other surgical options.
What is Keratoglobus?
Abstract Keratoglobus is a rare noninflammatory corneal thinning disorder characterised by generalised thinning and globular protrusion of the cornea. It was first described as a separate clinical entity by Verrey in 1947.
What is the Keratoglobus tuck procedure?
Recent additions of techniques specifically for keratoglobus include the “tuck procedure”, whereby a 12 mm corneo-scleral donor graft is taken and trimmed at its outer edges. A host pocket is formed at the limbal margin and the donor tissue is “tucked” into the host pocket.
What are the risk factors for keratoglobus?
However, associations between keratoglobus and disorders such as Ehlers-Danlos type VI, Marfan syndrome, and the blue sclera syndrome indicate that the etiology may result from defects in collagen synthesis. No risk factors have been identified.