Where do skin grafts come from?
The most common sites of harvest for skin grafts are the buttocks and inner thigh, areas which are usually hidden and therefore cosmetically less important. A skin graft is a surgical procedure in which a piece of skin is transplanted from one area to another.
Do they use pig skin for skin grafts?
Xenograft or heterograft is skin taken from a variety of animals, usually a pig. Heterograft skin became popular because of the limited availability and high expense of human skin tissue. Wound coverage using heterograft is a temporary covering used until autograft.
What is TheraSkin made from?
What is TheraSkin? TheraSkin is an all human bioactive split thickness skin allograft with living cells, growth factors, and a native extracellular matrix.
Who invented skin grafts?
Following the revolutionary work by the Swiss doctor Jacques-Louis Reverdin in 1869, the first skin graft was performed in Denmark in 1870. Skin grafts were used to treat burn wounds until World War I but due to poor results, the method was abandoned for ointment treatments.
What are the three types of skin grafts?
There are different types of grafts according to their origin, thickness and form. There are 3 main types of graftsthat are used to cover wounds: Split-thickness skin grafts, full-thickness skin grafts and composite grafts. Each of them has specific indication and has a unique technique for harvesting.
What is a porcine graft?
Skin graft, porcine: A skin graft in which pig skin is used. Like grafts from human donors, porcine grafts are usually just a short-term protective measure.
What can pig skin be used for?
Pigskin is a type of leather, commonly used for many items such as clothing, rarities, handbags, book covers, accessories and more. Pigskin leather is ranked fourth in the world’s total leather production, after its close comparison such as cow, sheep and goat leather.
What is the role of porcine skin in wound care?
Porcine skin serves as a relevant model for wound care. The skin has comparable thickness, hair follicle density, and wound closure via reepithelialization.
What is porcine skin testing?
Porcine skin testing is commonly used to test formulations or compounds that are applied to the skin (e.g., presurgical products). We can track efficacy against host flora or seed the skin with known pathogens and track how they respond to the compound. We can apply this testing to large or small areas of skin.
How do we use porcine models to study inflammation?
We use our porcine skin model to study inflammation by testing the tissue for known biomarkers associated with inflammatory processes. We can apply experimental formulations onto large or small areas of skin and then harvest uniformly sized explants with a biopsy punch.
How do skin allografts work?
“Skin allografts mechanically protect the wound and provide biologic factors native to human skin, which may help stimulate the wound healing process. AlloSource’s process uses electron beam irradiation to yield a ready-to-use, shelf-stable graft with room temperature storage, eliminating the need for costly cryo freezers.