What tests are performed on CSF?
CSF analysis usually involves an initial, basic set of tests performed when CSF analysis is requested:
- CSF color, clarity and pressure during collection.
- CSF protein.
- CSF glucose.
- CSF cell count (total number of cells present)
- CSF differential cell count (numbers of different types of cells present)
What is a normal CSF?
In normal adults, the CSF volume is 90 to 200 mL [1]; approximately 20 percent of the CSF is contained in the ventricles; the rest is contained in the subarachnoid space in the cranium and spinal cord. The normal rate of CSF production is approximately 20 mL per hour.
Why CSF analysis is important?
The purpose of a CSF analysis is to diagnose medical disorders that affect the central nervous system such as meningitis, metastatic tumors, syphilis, hemorrhaging or multiple sclerosis.
What is the normal CSF pressure?
Results: The normal range of ICP measured by LP in adults in a typical clinical setting should now be regarded as 6 to 25 cmH2O (95% confidence intervals), with a population mean of about 18 cmH2O.
What is normal CSF pressure?
What is a Normal Opening Pressure? The normal range for CSF is reported differently in various sources, with most reporting a normal range of 7-18 cmH2O in adults,1 though some consider the normal range 5-25 cmH2O.
What is CSF used for?
The central nervous system (CNS) consists of the brain and spinal cord. Cerebrospinal fluid (CSF) is a clear, colorless liquid that surrounds and protects the CNS. It bathes the brain and spine in nutrients and eliminates waste products. It also cushions them to help prevent injury in the event of trauma.
What is normal WBC in CSF?
Normal CSF has very few WBCs (0–8/mm3). In the presence of an inflammatory response, WBCs increase. Inflammatory response situations include: Meningitis of all types.
What is high WBC in CSF?
An increase of white blood cells indicates infection, inflammation, or bleeding into the cerebrospinal fluid. Some causes include: Abscess. Encephalitis.
What happens if CSF pressure is high?
Intracranial hypertension means that the pressure of the fluid that surrounds the brain (cerebrospinal fluid or CSF) is too high. Elevated CSF pressure can cause two problems, severe headache and visual loss. If the elevated CSF pressure remains untreated, permanent visual loss or blindness may result.
What causes high CSF?
Common causes include: Aneurysm rupture and subarachnoid hemorrhage. Brain tumor. Encephalitis (irritation and swelling, or inflammation of the brain)