What is hyperuricosuria Huu?
Hyperuricosuria (HUU) is the excessive excretion of uric acid in the urine, which can cause stones in the bladder or kidneys. Stones are difficult to treat and surgery is often required to remove them.
How do you prevent hyperuricosuria in dogs?
Prevention strategies suggested for the management of urate uroliths in dogs with genetic hyperuricosuria include low purine diets (often achieved by feeding a low protein diet), urine alkalinisation, xanthine oxidase inhibitors, and increased water intake [4].
Do all Dalmatians have hyperuricosuria?
All Dalmatians have hyperuricosuria and thus all are prone to develop urate stones. Males are more likely to be affected than females.
What is Hua Dalmatian?
HUA means high uric acid. These dogs are prone to forming kidney/bladder stones and they need a diet low in purines, lots of water and frequent potty breaks to prevent this problem.
What causes hyperuricosuria?
The most common cause of hyperuricosuria is increased dietary purine intake, but many other hereditary or acquired factors (eg, gout) may result in this condition. Individuals with hyperuricosuria may develop uric acid or calcium oxalate stones due to supersaturation of urine with monosodium urate.
What does Huu mean in dogs?
Hyperuricosuria
Weimaraner Health Panel Hyperuricosuria (HUU) means elevated levels of uric acid in the urine. This trait predisposes dogs to form stones in their bladders or sometimes kidneys. These stones often must be removed surgically and can be difficult to treat.
What dog food is low in purines?
Naturediet’s Feel Good Chicken, Feel Good Fish, Feel Good Grain Free Chicken and Purely Chicken are all low in purine and therefore can offer a healthy complete and balanced meal for a dog requiring this type of diet.
What is hua and Lua puppies?
Each time one of these backcross Dalmatians (with low levels of uric acid, or LUA dogs) is bred to a purebred Dalmatian (with high levels of uric acid, or HUA dogs), about 50 percent of the puppies are LUA and 50 percent are HUA.
What is Lua hua?
HUA Dalmatians are often referred to by breeders as hu/hu – meaning they have two HyperUricosuria genes. LUA Dalmatians are referred to as N/hu (if they have one of the normal genes in question) or N/N (if they have two copies of the normal gene in question).
How is Hyperuricosuria treated?
A diet with high fluid intake, low sodium intake, and moderate protein intake is recommended. Low sodium intake reduces sodium urinary excretion, which reduces monosodium urates that are catalysts for hyperuricosuric calcium nephrolithiasis.
How much is a Huu test?
Cost per sample is £45.00.
Is the hyperuricosuria mutation associated with urate urolithiasis?
These samples were tested and determined to be homozygous for the hyperuricosuria mutation, providing further evidence that the hyperuricosuria mutation is correlated with urate urolithiasis in these breeds.
What is the phenotype of hyperuricosuria?
Phenotype: Hyperuricosuria is characterized by elevated levels of uric acid in the urine and can lead to the formation of bladder/kidney stones.
Is hyperuricosuria hereditary in dogs?
These stones often must be removed surgically and can be difficult to treat. HUU is inherited as a simple autosomal recessive defect. A mutation in exon 5 of the gene Solute carrier family 2, member 9 (SLC2A9) has been found to be associated with hyperuricosuria in dogs.
What is the cause of hyperuricosuria?
Uric acid is the end-product of purine metabolism and hyperuricosuria often results from a diet high in purine intake. Animal protein from beef, poultry and fish contain high amounts of purines [66].